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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight-loss in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err on the side of caution and permit the FDA do its job and demand some research be done in order that the public understands the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on the medications.

Researchers discovered that participants using this drug to get a year, dropped excess weight within four weeks and have kept the load off through the 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of several active ingredient, which can make them more potent and safer.

Combo-pilling will be the newest fad or even better the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that by right now there aren't any long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise blood pressure levels and pulse rate, and mustn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

From a psychiatric perspective, evidence shows that the ordinary neural mechanism for goal-directed behavior continues to be hijacked with the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus and also the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).

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